goolhealth 1 year ago
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Middleweight weight loss may indicate dementia

Sharp weight loss in a middle-aged man can be the impetus for the development of dementia in the future. This conclusion was made by scientists from the Mayo Clinic (Minnesota, USA)

Scientists investigated how weight loss in a person whose age was in the range between 40 and 70 years, is associated with intellectual activity. Experts noted that the causes for which appetite is reduced and weight loss occurs in middle age can be problems known as “anorexia of aging”, which is considered the forerunner of dementia.

Researchers conducted a study of 1900 medical records of patients who have experienced weight loss at this age. They found that a loss of more than 5 kg in 10 years of life increases the risk of developing dementia by 24%. Scientists note that depression and apathy, which are early symptoms of dementia, can sometimes cause people to lose weight for several years before the clinical picture of the disease is visible. On this basis, the scientists noted that a strong weight loss by middle-aged people should alert the attending physician.

A team of scientists analyzed 1895 medical records of patients over the age of 70 years. All had no signs of senile dementia. Five years later, a similar analysis revealed that 524 people from this group had progressed dementia. Assessing the change in the weight of these patients in middle years, scientists pointed out that older people with dementia lost an average of 2 kg of weight, while those who retained cognitive activity lost no more than 1.2 kg.

The findings of the scientific work published in the publication «JAMA Neurology».

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